منابع مشابه
The antagonism of nondepolarizing neuromuscular blockade.
The antagonism of the nondepolarizing neuromuscular blockade is accomplished many times in a given day. Fortunately, the incidents of complications are low. If they do occur and are not recognized and treated properly, however, the results can be serious. In this article, the author reviews the curariform group of drugs, anticholinesterases, and anticholinergics, evaluating the antagonism of th...
متن کاملEdrophonium priming for antagonism of atracurium neuromuscular blockade.
Edrophonium administered in divided doses has been reported to accelerate antagonism of neuromuscular blockade, i.e., a "priming" effect. Since measured onset times can be affected by the type of stimulation used, this effect was studied using both train-of-four (TOF) and single twitch (ST) stimulation. During thiopentone-nitrous oxide-enflurane anaesthesia 20 adults were given atracurium 0.5 m...
متن کاملAntagonism of atracurium-induced neuromuscular blockade by neostigmine or edrophonium.
Antagonism of atracurium-induced neuromuscular blockade by neostigmine or edrophonium has been studied using the tetanic (50 Hz) and train-of-four (2 Hz) or single twitch responses of the adductor pollicis muscle in 22 anaesthetized patients. A further nine patients not given an anticholinesterase acted as a control group. In two groups (six patients for each anticholinesterase) in whom antagon...
متن کاملAntagonism of profound neuromuscular blockade induced by vecuronium or atracurium. Comparison of neostigmine with edrophonium.
The effectiveness of neostigmine 0.07 mg kg-1 and edrophonium 0.8 mg kg-1 as antagonists of profound neuromuscular blockade induced by vecuronium 0.1 mg kg-1 or atracurium 0.5 mg kg-1 was studied in 59 healthy patients. The antagonists were administered 5 min after total ablation of the twitch response and the end-point of recovery was a train-of-four ratio of 70%. In 30 patients given vecuroni...
متن کاملUse of neostigmine in the antagonism of residual neuromuscular blockade produced by vecuronium.
Recovery from neuromuscular block produced by vecuronium was studied in 50 patients using electromyography and the train-of-four technique. Twenty patients received neostigmine 2.5 mg, 10 when the initial response of the train-of-four was 50% of control and 10 when it was 10%. Neostigmine 5 mg was investigated in a similar manner and in 10 patients spontaneous recovery was studied. In all patie...
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ژورنال
عنوان ژورنال: Anaesthesia
سال: 1988
ISSN: 0003-2409,1365-2044
DOI: 10.1111/j.1365-2044.1988.tb05654.x